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Showing posts with label herbal. Show all posts
Showing posts with label herbal. Show all posts

The Elixir (a film by Kimo Stamboel)

October 28, 2025

The Elixir
The Elixir

Kimo Stamboel directs the first Indonesian zombie-themed film, The Elixir (Abadi Nan Jaya). The Elixir (Abadi Nan Jaya) film first launched on Netflix Indonesia on October 23, 2025, which also offers English and Japanese dubbed audio. The Elixir (Abadi Nan Jaya) is set in Wanirejo Village, a fictive location in Yogyakarta, where the center of the film focuses on the family who owns Pabrik Jamu Wani Waras (Wani Waras Herbal Medicine Factory). The film itself was actually shot in Piyungan village, Bantul, Yogyakarta.

Top Movies on Netflix on November 1, 2025
Top Movies on Netflix on November 1, 2025, provided by FlixPatrol.

The Elixir (Abadi Nan Jaya) uses more than 200 extra cameos who play zombie crowds. The combination of the zombie makeup artist's work and special effects has made the film the most watched on Netflix in its first week. After all, it is the first Indonesian zombie-themed genre, unlike previous Indonesian ghost-themed films.

The Javanese language is used in the film, with most dialog using Bahasa Indonesia. I think it is quite funny hearing Rudi scream dog as a profanity to curse at the zombie who is chasing him when it is dubbed in English audio. Jamu Abadi Nan Jaya from the sample ANJ 23B is said to use natural ingredients from the Kantong Semar (Nepenthes Linn.).

Kantong Semar (Nepenthes Linn.)
Kantong Semar (Nepenthes Linn.)

Kantong Semar (Nepenthes Linn.) is a carnivorous plant that catches and digests insects. This plant is characterized by a tube-shaped pouch or trap located at the tip of its leaves. A reason for the zombies becoming numb when it rains and catching the falling raindrops.

The ending of the film implies that there will be a second sequel to the film, which would certainly be more rational if the location setting was expanded to at least cover the entirety of Indonesia being affected by the zombie outbreak before heading overseas.


The Elixir (Abadi Nan Jaya) Official Trailer
YouTube video is courtesy of Netflix Indonesia

Plot

The scene opens 5 hours later at a wedding reception at the village head's house. Rahman (Ardit Erwandha), who was still in full police uniform, chased after Ningsih (Rr. Claresta Taufan Kusumarina), who half ran and rushed to the kitchen, leaving him behind upon seeing him. Ningsih questioned Rahman's determination about when he would propose to her while washing the dishes. Behind Ningsih, Rahman took out his ring to propose to her in the kitchen. However, Rahman canceled his proposal when his commander called and asked him to return to the police station.

Shortly after Rahman left the wedding reception at the village head's house, a car passed by on the road where the wedding tent had been set up and knocked over the guest chairs. The car stopped after hitting a pickup truck carrying a sound system for the wedding reception. Many guests fell due to the speed of the car. The village head (Stephanus Tjiproet) then ran to the stopped car and knocked on the window. When the car door was opened, inside, Aris (Kiki Narenda), the Sadimin (Donny Damara) family driver, who had begun to transform into a monster, quickly pounced on the village head, knocked him down, and bit him on the edge of the rice field.

5 Hours Earlier

Wani Waras Factory
Wani Waras = Dare to be healthy

At Pabrik Jamu Wani Waras, the herbal medicine scientist is asking his crew to deliver the two samples of the new product of herbal medicine that they call Abadi Nan Jaya (Eternity Glorious), which have not been tested by the Indonesian BPOM (National Agency of Drug and Food Control). One for the owner, Sadimin, and the other for his business partner in Jakarta, Grace (Karina Suwandhi).

Receiving the sample from the factory, Sadimin drinks it without hesitation. Returning from the bathroom after taking a shower, he is surprised that he no longer needs glasses and his gray hair has also turned black again. His wrinkled, aged skin is no longer visible. His wife, Karina (Eva Celia Latjuba), noticed the change in her husband's looks and then asked Sadimin. Thanks to this new formula of Jamu Abadi Nan Jaya. It makes me young again, said Sadimin.

Best Friend as Mother-in-Law

Kenes, Karina & Bambang
Kenes, Karina & Bambang (From left to right)

That morning, Kenes (Mikha Tambayong), with her husband Rudi (Dimas Anggara) and their only child Raihan (Varen Arianda Calief), is visiting Sadimin's residence from Jakarta by car. Kenes is Sadimin's youngest daughter, who is also his wife, Karina's best friend from high school. While Bambang (Marthino Lio), Sadimin's elder son, is a toy collector and an online gamer that never left his father's house. Kenes's and Karina's relationship was broken after Karina married Sadimin shortly after Kenes's mother passed away.

Kenes and Rudi's visit to Sadimin's house was to finalize the sale of the factory, which Sadimin had previously mentioned. Sadimin's plans to retire from managing the factory and the lack of sales were the primary reasons for the sale. Meanwhile, Bambang, Kenes, and Rudi had other plans for the money that they would receive from the factory sale's deal. Bambang wants to buy a new car. Kenes and Rudi are getting a divorce, and Kenes will use the money to start a new business. But all of their plans go away after Sadimin states that he refuses to sell the factory. Both Sadimin's children questioned him angrily. "It's all because of this new formula of Jamu Abadi Nan Jaya that will make the factory great again, said Sadimin.

The First Bite Zombie

Sadimin turns into a zombie
Sadimin turns into a zombie.

Sadimin is stressed after having an intense debate with both of his children and his son-in-law. He feels an itch on his skin and suddenly gets a seizure. All of them are in a panic after noticing that Sadimin is no longer breathing.

Raihan screams for his mother when he first sees his grandfather turn into a monster. Pardi (Hingka Moedra), the family servant, is surprised to see his master suddenly change, who then jumps on him and bites him. Aris's effort to rescue Pardi is in vain when Sadimin suddenly jumps on him. Lying on the floor, Sadimin, on top of Aris's body, tries to bite him but vomits blood instead all over Aris's face.

Bambang comes to rescue Aris but ends up in the same position as Aris. Having his new toy in his hand, Bambang shoots his father's head with a plastic arrow. Rudi then asks Aris to drive to the nearest precinct to report the incident in their house. Meanwhile, the other family servant treats the injured Pardi in the kitchen.

Assault on Precinct Wanirejo

Assault on Precinct Wanirejo
Assault on Precinct Wanirejo.

After the wedding incident, which made more infected zombie crowds, which was transmitted by Aris. The crowds occupy the Precinct Wanirejo until late at night, after the help from the Sleman Police Resort has also been attacked by the crowds on the way to the precinct.

On that same night, Rahman finally manages to propose to Ningsih by putting the ring on Ningsih's finger while surrounded by zombie crowds who bite both of them. Bambang sacrifices himself to save Kenes, Karina, and Raihan by blowing up the whole precinct.

Kenes takes a bullet through her head
Kenes takes a bullet through her head.

On the way escaping the remaining zombie crowds, Kenes notices that her hand has also been bitten. She then asked Karina to take care of her only son. Kenes takes a bullet through her head when her face is starting to show the zombie transformation.

Karina and Raihan in the distance followed by Pardi, the 1st bite zombie, leaving Wanirejo village
Karina and Raihan in the distance followed by Pardi, the 1st bite zombie, leaving Wanirejo village.

In the morning, Karina and Raihan manage to leave the village using Rahman's motorbike, followed by Pardi walking behind them. Meanwhile, in Jakarta, Grace, Sadimin's business partner, tries to call Sadimin shortly after drinking the sample ANJ 23B from the factory. The film ended with a blurry image showing Grace's youth transformation after leaving the bathroom.

The Elixir (Abadi Nan Jaya)
The Elixir (Abadi Nan Jaya)


Update: November 2, 2025.

From The Bitter Taste of Bratawali

November 07, 2013

Tinospora cordifolia
Bratawali (Tinospora cordifolia)
Image from Wikimedia.org

Bratawali (Tinospora cordifolia) is a well known plant in Indonesia. Bratawali is often used as jamu paitan, or Javanese traditional herbal drink, which has a bitter taste. When making jamu paitan, the stems extract of bratawali, is often mixed with mint leaves.

Common bratawali names include, brotowali, putrawali, daun gadel (Javanese), andawali (Sundanese), antawali (Balinese), shen jin teng, kuan jin teng (Chinese), guduchi, guluchi, amritavalli, amrta, cinnodbhava, gulvel (India). Bratawali is common used in Ayurvedic, and Traditional Chinese Medicine (TCM), as a herbal remedy.

The Javanese's jamu paitan makers often promote bratawali, as a herbal remedy for lowering the risk of having diabetes, and also as a blood cleansing agent. Below are some studies which demonstrated the effects of bratawali.

Animal Studies

Study by Department of Anatomy, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia, was conducted to determine the effect of ethanolic extract of the dried stems of bratawali, in a male rat model of hepatic fibrosis, caused by the hepatotoxin, thioacetamide.

The results showed a significant increase in the activity of liver enzymes, bilirubin and G-glutamyl transferase and gross. The histopathological changes were also determined. (Kadir FA, et al. 2011)

Diabetes mellitus often leads to disability from vascular complications and neurological complications. A study by Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan, was investigated the hypoglycemic actions of borapetoside C isolated from bratawali.

Three groups of mice were used in the study, normal mice, type 1 diabetes mellitus mice, and type 2 diabetes mellitus mice. Overall, the study proved that borapetoside C can increase glucose utilization, delayed the development of insulin resistance and enhanced insulin sensitivity.

The activation of IR-Akt-GLUT2 expression, and the enhancement of insulin sensitivity, may contribute to the hypoglycemic action of borapetoside C, in diabetic mice. (Ruan CT, et al. 2012)

Recent follow up study by Ruan CT, et al. aimed to explore the hypoglycemic effects of borapetoside A, the most active diterpenoid among others (borapetosides B, and C), which isolated from the ethanol extract of bratawali.

The study resulted that borapetoside A was shown to increase the glycogen content and decrease the plasma glucose concentration, in a concentration, or dose-dependent manner, both in vitro, and in vivo.

The hypoglycemic effects in the normal mice, and the mice with type 2 diabetes mellitus were associated with the increases of the plasma insulin levels. But, the insulin levels remained unchanged in the mice with type 1 diabetes mellitus. (Ruan CT, et al. 2013)

A study by Department of Physiology, Faculty of Science, Prince of Songkla University, Hat-Yai, Songkhla, Thailand, was aimed to identify the active components of bratawali extract, and to investigate the mechanisms of the actions, on blood pressure, and heart rate, in anesthetized rats.

Five active compounds, adenosine, uridine, salsolinol, higenamine, and tyramine, which were isolated from bratawali, acted in concert on the cardiovascular system of anesthetized rats. (Praman S, et al. 2012)

Follow up study by Praman S, et al. resulted that bratawali extract caused an increase in the force of contraction of the electrical field stimulated left atrium. The study concluded that crude extracts of bratawali exert a positive inotropic effect, on the electrical field stimulated isolated left atria.

The results were also from the concerted actions of five bratawali bioactive compounds: higenamine, salsolinol, tyramine, adenosine and uridine. (Praman S, et al. 2013)

Human Study

Although several studies using rats or mice were successfully, but not in human study. So far, I only managed to find a study by Department of Medicine, Ramathibodi Hospital, Faculty of Medicine, Mahidol University, Bangkok, Thailand. The study aimed to determine the effects of bratawali on serum glucose, and insulin levels, in healthy subjects, and patients with type 2 diabetes mellitus.

Serum from ten healthy subjects, and ten diabetic participants, who had fasted overnight. The serums were obtained every 30 to 60 minutes during the 3 hours of continued fasting, and during the 3 hours after ingestion of 75g of glucose. With or without ingestion of 125g, or 250g of bratawali dry powder capsule. Glucose, and insulin levels were analyzed. The areas under the curve for mean serum glucose, and insulin levels, were also calculated.

Both healthy and diabetic participants were not significantly different between with, or without bratawali dry powder capsule. The results suggested that bratawali ingestion cannot affect serum glucose, and insulin levels, in healthy subjects, or patients with type 2 diabetes mellitus. (Klangjareonchai T, et al. 2012)

Further studies using human subjects are needed to give more valuable information, in regarding the health benefits of bratawali.



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biXa Guduchi Powder Sandhu's Guduchi
 

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