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Showing posts with label CHD. Show all posts
Showing posts with label CHD. Show all posts

Link Between Passive Smoker and Lung Cancer

September 14, 2013

A chest X-ray showing a tumor in the lung (marked by arrow)
A chest X-ray showing a tumor in the lung (marked by arrow).

Lung cancer, an abnormal and uncontrolled growth of the cells in tissues of the lung, is the most common cancer in the world. I had described this in my earlier post, that lung cancer contributed 12.7%, or 1,608,055 new cases, in 2008. The death rate was 18,2%, or 1,376,579 cases of cancer death worldwide.

Cigarette smoking causes mostlung cancers. The more cigarettes to smoke per day, and the earlier age of starting to smoke, the greater the risk of getting lung cancer. Other risks include, high levels of pollution, radiation, asbestos exposure, and first degree family history of any cancers especially lung cancer, may also increase the risk.

The most common symptoms of lung cancer, include:

  • A cough that does not heal, and even gets worse by coughing up blood.
  • Wheezing, or hoarseness, due to shortness of breath, a breathing difficulty, which involves a sensation of difficult, or uncomfortable breathing, or a feeling of not getting enough air.
  • Chest pain, discomfort or pain that you feel anywhere, along the front of your body, between your neck and upper abdomen, that does not heal.
  • Regular problems of having pneumonia, or bronchitis.
  • Swelling of the neck and face.
  • Suddenly of having weight loss, due to loss of appetite.
  • Always suffering from fatigue, although was not doing any hard works.

There are many types of lung cancer. Each type of lung cancer is treated differently, because the cancer cells grow, and spread in different ways. Treatments depend on the stage, in which include chemotherapy, radiation therapy, and surgery. (MedlinePlus)

Link Between Environmental Tobacco Smoke and Lung Cancer

Passive smokers, or second hand smokers, are people who are exposed by environmental tobacco smoke from an active smoker. Environmental tobacco smoke is also known as pollutants from smoker's lung.

Exposure to environmental tobacco smoke, is generally believed to increase the risk by 25%, of coronary heart disease (CHD), and lung cancer among never smokers. The increased risk is based primarily on meta analysis, and is still controversial due to methodological problems. A researcher, James E. Enstrom, with his associate professor, Geoffrey C. Kabat, was shocking the world, when British Medical Journal published his study, in 2003.

The study was based on cancer prevention study (CPS I) conducted by the American Cancer Society, among 118,094 adults, in 1959, and the follow up study until 1972. Enstrom then conducted the extended follow up, at the University of California, LA, until 1999, with focusing only on the 35,561 never smokers, who had a spouse, in the study, with known smoking habits.

The large study of Californians, which followed for 40 years, had found that environmental tobacco smoke was not associated with CHD, or lung cancer mortality, at any level of exposure. The study suggested that the effects of environmental tobacco smoke, particularly for CHD, are considerably smaller than generally believed.

Moreover, active cigarette smoking was confirmed as a strong risk factor for CHD, lung cancer, and chronic obstructive pulmonary disease (COPD), most commonly disease caused by tobacco smoke, such as, emphysema, and chronic bronchitis. (Enstrom JE, et al. 2003)

Smoker who lived until 95 Years of Age

My great grandfather from my mother side, was born in 1902. He was known as a heavy smoker by his sons, daughters, grandchildren, and great grandchildren. He died in 1997 at the age of 95 years, due to aging, and not from any diseases. My living grandmother, who was born in 1931, is the second daughter of my great grandfather.

In December 26, 1950, my grandparent was married. My grandparent who had just celebrated 62nd anniversary last year, are non smokers. After 82 years of living, my grandmother was never having any symptoms of CHD, or lung cancer. Also with my living grandmother elder sister (two years of age older), who took care of my great grandfather since the death of my second great grandmother, in 1987 (my first great grandmother died in 1957), was never having any symptoms of CHD, or lung cancer.

From the first marriage, my great grandfather had six daughters and four sons. My great grandfather did not have any children from the second marriage. Seven out of ten children of my great grandfather, are still living until I write this post. The seventh daughter died at a baby age.

Two sons, the third and forth son, who were also a heavy smoker, died because of lung cancer. I never knew the forth son of my great grandfather, because he died when my mom was still carrying me in pregnancy, in 1980. The third son died in 1998, a year after the death my great grandfather.

Then, you might wonder about me. Do I also a smoker? Yes, I do. Until now, I am the only great grandchildren who is an active smoker, after my elder cousin quitted smoking four years ago. Yes, I know the risk of smoking tobacco, and I want to quit smoking.

I found very hard for me to quit on smoking. Again, you might say, there is a way when there is a will. Perhaps someday, I will stop smoking. I started to smoke since I was graduate from high school, due to a broken heart. What? A broken heart can make people started to smoke? Infact, a broken heart can make people conduct a suicide.

Although, there was a dangdut song lyrics that said, better to have a toothache than a broken heart. But, for me, I prefer to have a broken heart than having a toothache. It's because you can still go to bed and sleep, although you had a broken heart. But, you could never get to sleep if you had a toothache

The Obesity Epidemic

August 15, 2013

Fat Guys

Obesity and Diabetes

Obesity is often associated with the high risk of having chronic diseases, such as, diabetes mellitus, and cardiovascular diseases. And then, thin people or vegetarians may have a lower risk of diabetes? No. Obesity may not be the main factor.

A healthy lifestyle will determine the quality of human health. Even in a vegetarian, who is also doing regular exercises, may not lower the risk of diabetes, if the main cause is genetic. It is a fact that, human genes, and family history of diabetes, are associate with the risk of diabetes.

Clinical controlled trials had shown solid evidence that type 2 diabetes is a disease of fatness. A five % of weight loss is sufficient to prevent most obese subjects with impaired glucose tolerance, in developing type 2 diabetes. Type 2 diabetes is obesity dependent, and obesity is well understood aetiology (study of causation), as the main cause of type 2 diabetes. (Astrup A, et al. 2000)

However, ask yourself!
How many times you met with an obese Indian, or Chinese?

An update 2012 data, from International Diabetes Federation showed that, there were 33.4 million men, and 29.6 million women with diabetes, in India. Also, there were 51.5 million men, and 40.8 million women with diabetes, in China.

While in my country of Indonesia, from about 300 million population, there were 3.2 million men, and 4.4 million women with diabetes, aged 20 to 79 years. In the US, there were 12.2 million men, and 11.9 million women with diabetes. (IDF)

According to the article published in 2009, by the Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Colorado Denver, the US generations might have a shorter life expectancy than their parents, if the obesity epidemic is not controlled.

Because, 35.1% of adults in the US, were classified as obese. In children, obesity will continue to increase steadily. The study showed that obesity may become the most difficult public health issues in the US. (Catenacci VA, et al. 2009)

Link Between Obesity and Prostate Cancer

The US Health Professionals Followup Study reported an inverse association between obesity, and the risk of developing prostate cancer, in men under 60 years of age, or in those with a family history of prostate cancer. The study found that body mass does not appear to affect the performance of prostate specific antigen as a diagnostic test. But, a lower body mass is associated with a higher cancer detection rate, on a prostate biopsy.

Although, several mechanisms have been proposed to explain the link between obesity and prostate cancer, including, hormonal alterations, hyperinsulinemia (high levels of insulin in the blood), glucose intolerance (inability to metabolize glucose), elevated IGF (insulin-like growth factor, hormone which exert an effect on bone cell metabolism), and leptin (hormone made by fat tissue, that acts on brain to regulate food intake, and body weight) levels, but, the mechanism which explains the association between obesity, and prostate cancer remains unclear. (Amling CL. 2005)

However, an article which published two months earlier, supported the hypothesis, that obesity is inversely associated with prostate cancer risk, in middle aged men. The study used the interviews from 753 men, aged 40 to 64 years, that were diagnosed with prostate cancer between 1993 and 1996. (Porter MP, et al. 2005)

Obesity and Coronary Heart Disease

We cannot control from where we get our genes, and healthy lifestyle may not prevent us from getting diabetes. But, a healthy lifestyle may prevent us from getting coronary heart disease (CHD). High blood cholesterol, high blood pressure, overweight and obesity, are controllable risk factors of CHD.

A healthy diet and having regular exercise, can help maintaining a healthy weight, in which helps to control CHD risk factors. Five to ten % loss of body weight can lower the risk of CHD. Overweight children and teens are associated with the high risk of CHD, and may also have a shorter life expectancy than their parents, if their weight gain rates are not reduced. However, personally reducing calorie diets are not advised, unless approved by a physician. (NHLBI)



Image credit: Shakespeare's Monkey

 

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